The new bosses for The Binding of Isaac are spread throughout existing floors as well as the new areas included with the DLC. Some of these bosses are original to this expansion while others actually originated from the fan-made Antibirth expansion.
RELATED: The Binding of Isaac Creator Edmund McMillen Gives Update on The Legend of Bum-bo
Counting all of them, there is a total of 31 new bosses included with The Binding of Isaac: Repentance. Each of them will provide returning players with plenty of new challenges to face and new projectile patterns to learn in the heat of the moment.
Old Areas
While the new environments have their own unique bosses added, many of the pre-existing locations have gotten their own new bosses that players can enjoy before the new areas are unlocked. These bosses are:
Baby Plum
Areas found: The Basement, Cellar, and Burning Basement Base HP: 234
Bumbino
Areas found: The Caves Base HP: 385
Great Gideon
Areas found: The Caves, the Catacombs, and Flooded Caves Base HP: N/A (Wave-based fight similar to Greed Mode)
Tuff Twins
Areas found: The Caves, the Catacombs, and Flooded Caves Base HP: 35 (Tough exterior and must be exposed via bombs)
The Shell
Areas found: The Caves, the Catacombs, and Flooded Caves Base HP: 35 (Tough exterior and must be exposed via bombs)
Singe
Areas found: The Caves, the Catacombs, and Flooded Caves Base HP: 444
Reap Creep
Areas found: The Caves and the Depths Base HP: 690
The Pile
Areas found: The Caves, the Catacombs, Flooded Caves, and Necropolis Base HP: 580
Downpour/Dross
Two of the new floors added for this expansion are Downpour and Dross. Downpour can be unlocked after players defeat Hush at least three times with Dross being unlocked after players beat all the bosses in Downpour.
These two areas share some bosses with some only appearing in one or the other. The bosses for these areas are.
The Rainmaker
Areas found: Only in Downpour Base HP: 200
Lil Blub
Areas found: In both Downpour and Dross Base HP: 130
Min Min
Areas found: Only in Downpour Base HP: 280
Wormwood
Areas found: In both Downpour and Dross Base HP: 200
Clog
Areas found: Only in Dross Base HP: 420
Colostomia
Areas found: Only in Dross Base HP: 380
Turdlet
Areas found: Only in Dross Base HP: 190
Mausoleum and Gehenna
Two new alternatives for the Depths that have been added are the Mausoleum and Gehenna. These new areas have their own new bosses that are exclusive to them and they are:
The Siren
Areas found: Only in the Mausoleum Base HP: 666
The Heretic
Areas found: Only in the Mausoleum Base HP: 789
The Visage
Areas found: Only in Gehenna Base HP: 620
The Horny Boys
Areas found: Only in Gehenna Base HP: 707
Corpse
Corpse is a new alternate area for the Womb, Utero, and Scarred Womb levels that players can enter. This area has its own set of bosses that can be challenged including a new alternative for Mom’s Heart and It Lives. These bosses are:
Rotgut
Areas found: Corpse Base HP: 1800
Chimera
Areas found: Corpse Base HP: 1050
The Scourge
Areas found: Corpse Base HP: 950
Mother
Areas found: Corpse Base HP: 4222
WARNING: MAJOR SPOILERS BELOW.
Home
The true final area of The Binding of Isaac is Home, where the last bosses of the game lie. Defeating them will lead players to the game’s true ending which won’t be an easy job. These bosses are:
Dogma
Areas found: Home Base HP: 2400
Ultra Famine
Areas found: Home Base HP: 2000
Ultra Pestilence
Areas found: Home Base HP: 1800
Ultra War
Areas found: Home Base HP: 2000
Ultra Death
Areas found: Home Base HP: 2000
The Beast
Areas found: Home Base HP:
The Binding of Isaac is available on PC, Nintendo Switch, PlayStation 4, and Xbox One.
MORE: Everything You Need to Know About The Binding of Isaac: Repentance
Source: SlayXc2 | YouTube
